Ionis Pharmaceuticals, Inc. Common Stock — Institutional Ownership
Which tracked institutions hold IONS, and how they changed the position last quarter. Latest holdings as of Mar 31, 2026. Source: SEC 13-F filings.
45
Funds holding
$2208926700
Total value held
Buying
31 added/new · 11 reduced
| # | Institution | Value | Shares | Δ Shares | Change (QoQ) |
|---|---|---|---|---|---|
| 1 | Blackrock, Inc. | $784125524 | 10442476 | -205387 | -1.93% |
| 2 | State Street Corp | $300026901 | 3995564 | +20699 | +0.52% |
| 3 | Royal Bank Of Canada | $285477000 | 3801815 | — | NEW BUY |
| 4 | Goldman Sachs Group Inc | $127641511 | 1699847 | +629381 | +58.80% |
| 5 | Franklin Resources Inc | $118268500 | 1575023 | +253678 | +19.20% |
| 6 | Invesco Ltd. | $100413532 | 1269290 | +750220 | +144.53% |
| 7 | Morgan Stanley | $77080721 | 1026509 | +6603 | +0.65% |
| 8 | Northern Trust Corp | $65191562 | 868179 | +21461 | +2.53% |
| 9 | Bank Of America Corp /De/ | $63120538 | 840598 | +57019 | +7.28% |
| 10 | Ameriprise Financial Inc | $49570211 | 660144 | +61396 | +10.25% |
| 11 | Bank Of New York Mellon Corp | $38642620 | 514617 | -23269 | -4.33% |
| 12 | Blackrock, Inc. | $28904937 | 19190000 | +1825000 | +10.51% |
| 13 | Barclays Plc | $25521140 | 339874 | — | NEW BUY |
| 14 | Wells Fargo & Company/Mn | $22154355 | 280045 | -5248 | -1.84% |
| 15 | State Street Corp | $18051759 | 11900000 | -300000 | -2.46% |
| 16 | Raymond James Financial Inc | $17655219 | 235121 | -22089 | -8.59% |
| 17 | Nomura Holdings Inc | $13026613 | 173480 | — | NEW BUY |
| 18 | Sei Investments Co | $11806016 | 157222 | — | NEW BUY |
| 19 | Citigroup Inc | $9243213 | 116840 | -106413 | -47.66% |
| 20 | Citigroup Inc | $8551407 | 5384000 | — | NEW BUY |
| 21 | Citigroup Inc | $7013030 | 5119000 | — | NEW BUY |
| 22 | Nomura Holdings Inc | $6386917 | 85057 | — | NEW BUY |
| 23 | Janus Henderson Group Plc | $5120803 | 68191 | — | NEW BUY |
| 24 | Goldman Sachs Group Inc | $3705375 | 2460000 | +458000 | +22.88% |
| 25 | Royal Bank Of Canada | $3266000 | 2160000 | — | NEW BUY |
| 26 | Invesco Ltd. | $2382450 | 1500000 | — | NEW BUY |
| 27 | Barclays Plc | $2355540 | 1558000 | — | NEW BUY |
| 28 | Wells Fargo & Company/Mn | $2343881 | 1474000 | -5389000 | -78.52% |
| 29 | Bank Of Montreal /Can/ | $1996269 | 26585 | — | NEW BUY |
| 30 | Bank Of Montreal /Can/ | $1911042 | 1264000 | — | NEW BUY |
| 31 | Bank Of America Corp /De/ | $1476125 | 980000 | -6633000 | -87.13% |
| 32 | Pnc Financial Services Group, Inc. | $1017095 | 13545 | -271 | -1.96% |
| 33 | Wells Fargo & Company/Mn | $972565 | 706000 | -20000 | -2.75% |
| 34 | Truist Financial Corp | $964606 | 12846 | +187 | +1.48% |
| 35 | Fifth Third Bancorp | $826806 | 11011 | +3123 | +39.59% |
| 36 | M&T Bank Corp | $644142 | 8150 | +2140 | +35.61% |
| 37 | Principal Financial Group Inc | $527056 | 7019 | +3680 | +110.21% |
| 38 | Regions Financial Corp | $459701 | 6122 | +33 | +0.54% |
| 39 | Us Bancorp \De\ | $378978 | 5047 | -94 | -1.83% |
| 40 | Marex Group Plc | $271075 | 3610 | — | NEW BUY |
| 41 | Sei Investments Co | $158156 | 105000 | — | NEW BUY |
| 42 | Morgan Stanley | $141588 | 94000 | — | Held |
| 43 | Truist Financial Corp | $117216 | 73000 | — | Held |
| 44 | Atlantic Union Bankshares Corp | $15822 | 200 | — | Held |
| 45 | Amalgamated Financial Corp. | $1183 | 31934 | — | NEW BUY |
Aggregated across tracked institutional filers. Reported quarterly on SEC Form 13-F and may lag. For research only — not investment advice.