Ionis Pharmaceuticals, Inc. Common Stock — Institutional Ownership

Which tracked institutions hold IONS, and how they changed the position last quarter. Latest holdings as of Jun 30, 2026. Source: SEC 13-F filings.

38
Funds holding
$2973222985
Total value held
Buying
28 added/new · 9 reduced
# Institution Value Shares Δ Shares Change (QoQ)
1 Blackrock, Inc. $866531324 22129660 -7502816 -25.32%
2 Royal Bank Of Canada $490365000 6282479 +320664 +5.38%
3 State Street Corp $367067891 19359848 +3464284 +21.79%
4 Jpmorgan Chase & Co $243699435 3554717 -4455850 -55.62%
5 Goldman Sachs Group Inc $167297540 2109945 +410098 +24.13%
6 Barclays Plc $131460153 1899136 +1262 +0.07%
7 Franklin Resources Inc $128717601 1623377 +48354 +3.07%
8 Morgan Stanley $101605768 1281444 +254935 +24.84%
9 Invesco Ltd. $88860858 1120707 +1120707 NEW BUY
10 Northern Trust Corp $72440137 913610 +45431 +5.23%
11 Bank Of America Corp /De/ $62717591 790990 -49608 -5.90%
12 Ubs Group Ag $49751438 756874 +756874 NEW BUY
13 Bank Of New York Mellon Corp $43011166 542454 +27837 +5.41%
14 Nomura Holdings Inc $39452246 497569 +239032 +92.46%
15 Citigroup Inc $20595665 445046 -5055794 -91.91%
16 Wells Fargo & Company/Mn $18925063 861213 -4310640 -83.35%
17 Raymond James Financial Inc $18819309 237348 +2227 +0.95%
18 Stifel Financial Corp $16094533 202983 +202983 NEW BUY
19 Sei Investments Co $10138929 127868 -29354 -18.67%
20 Bank Of Montreal /Can/ $6991952 88182 +61597 +231.70%
21 Bank Of Nova Scotia $5435171 68548 +68548 NEW BUY
22 Ameriprise Financial Inc $5368490 67705 +67705 NEW BUY
23 Janus Henderson Group Plc $5120803 68191 +68191 NEW BUY
24 Jefferies Financial Group Inc. $3065748 38665 +38665 NEW BUY
25 Prudential Financial Inc $2801950 35338 +70 +0.20%
26 Allstate Corp $1343410 16943 +16943 NEW BUY
27 Truist Financial Corp $1228923 87068 +1222 +1.42%
28 Pnc Financial Services Group, Inc. $1124728 14185 +640 +4.72%
29 Marex Group Ltd $807886 10189 +6579 +182.24%
30 Fifth Third Bancorp $797733 10061 -950 -8.63%
31 M&T Bank Corp $595407 7510 -640 -7.85%
32 Us Bancorp \De\ $504760 6366 +1319 +26.13%
33 Regions Financial Corp $444341 5604 -518 -8.46%
34 Zions Bancorporation, National Association /Ut/ $16968 214 +214 NEW BUY
35 Atlantic Union Bankshares Corp $15858 200 Held
36 First Horizon Corp $4916 62 +62 NEW BUY
37 Amalgamated Financial Corp. $1183 31934 +31934 NEW BUY
38 Southstate Bank Corp $1111 14 +14 NEW BUY

Aggregated across tracked institutional filers. Reported quarterly on SEC Form 13-F and may lag. For research only — not investment advice.