Upstream Bio, Inc. — Institutional Ownership

Which tracked institutions hold UPB, and how they changed the position last quarter. Latest holdings as of Jun 30, 2026. Source: SEC 13-F filings.

18
Funds holding
$51892539
Total value held
Buying
15 added/new · 3 reduced
# Institution Value Shares Δ Shares Change (QoQ)
1 Blackrock, Inc. $25973237 3753358 +382669 +11.35%
2 Jpmorgan Chase & Co $7013464 1012044 +549043 +118.58%
3 State Street Corp $5302955 766323 +60973 +8.64%
4 Morgan Stanley $3630453 524632 -27977 -5.06%
5 Bank Of America Corp /De/ $2710993 391762 +343302 +708.42%
6 Northern Trust Corp $2057634 297346 +36354 +13.93%
7 Goldman Sachs Group Inc $1708666 246917 -69670 -22.01%
8 Ubs Group Ag $1624221 234714 +234714 NEW BUY
9 Bank Of New York Mellon Corp $593369 85747 +4364 +5.36%
10 Invesco Ltd. $369508 53397 +53397 NEW BUY
11 Citigroup Inc $279145 40339 +33390 +480.50%
12 Wells Fargo & Company/Mn $204119 29497 +11095 +60.29%
13 Barclays Plc $202120 29208 +4488 +18.16%
14 Sei Investments Co $138580 20026 +20026 NEW BUY
15 Ameriprise Financial Inc $72570 10487 +10487 NEW BUY
16 Royal Bank Of Canada $7000 1091 +1091 NEW BUY
17 Pnc Financial Services Group, Inc. $2678 387 +387 NEW BUY
18 Us Bancorp \De\ $1827 264 -326 -55.25%

Aggregated across tracked institutional filers. Reported quarterly on SEC Form 13-F and may lag. For research only — not investment advice.