Upstream Bio, Inc. — Institutional Ownership

Which tracked institutions hold UPB, and how they changed the position last quarter. Latest holdings as of Mar 31, 2026. Source: SEC 13-F filings.

13
Funds holding
$54001843
Total value held
Buying
8 added/new · 5 reduced
# Institution Value Shares Δ Shares Change (QoQ)
1 Blackrock, Inc. $30336201 3370689 +26185 +0.78%
2 State Street Corp $6348150 705350 -613876 -46.53%
3 Morgan Stanley $4973481 552609 +430541 +352.71%
4 Invesco Ltd. $4430500 163186 +145996 +849.31%
5 Goldman Sachs Group Inc $2849283 316587 -16894 -5.07%
6 Northern Trust Corp $2348928 260992 +24193 +10.22%
7 Wells Fargo & Company/Mn $998957 36794 +11634 +46.24%
8 Bank Of New York Mellon Corp $732447 81383 -3470 -4.09%
9 Bank Of America Corp /De/ $436140 48460 -37924 -43.90%
10 Barclays Plc $222480 24720 NEW BUY
11 Citigroup Inc $188665 6949 -35088 -83.47%
12 Franklin Resources Inc $131301 14589 NEW BUY
13 Us Bancorp \De\ $5310 590 +44 +8.06%

Aggregated across tracked institutional filers. Reported quarterly on SEC Form 13-F and may lag. For research only — not investment advice.