Spyre Therapeutics, Inc. (SYRE)

Typically moves ±3.79% on earnings

EARNINGS ANALYTICS

event_note Approx. Next Earnings: ~2026-08-11 APPROXIMATE

Spyre Therapeutics, Inc. (SYRE) has a 42-report earnings history dating back to May 19, 2016. Its average absolute post-earnings move is ±3.79%, and 54.8% of those reactions were positive. Its largest post-earnings gain was +14.28% (Feb 19, 2026) and its largest decline was -6.56% (Nov 03, 2022). The next earnings report is predicted for 2026-08-11 (approximate).

Earnings reactions

How SYRE moved on each past earnings report.

Up Down

Earnings Impact

Total Earnings

Avg Abs. Movement

±3.79%

Positive %

54.8%

Negative %

45.2%

Historical Earnings Statistics

Date	Timing	Earnings move	SEC Filing
May 05, 2026	☀ PRE	+2.73%	open_in_new
Apr 13, 2026	☽ POST	+1.17%	open_in_new
Feb 19, 2026	☽ POST	+14.28%	open_in_new
Nov 04, 2025	☽ POST	-0.57%	open_in_new
Aug 05, 2025	☽ POST	-5.39%	open_in_new
May 08, 2025	☽ POST	+9.64%	open_in_new
Feb 27, 2025	☽ POST	+7.24%	open_in_new
Nov 07, 2024	☽ POST	+5%	open_in_new
Aug 07, 2024	☽ POST	+2.85%	open_in_new
May 09, 2024	☽ POST	+4.94%	open_in_new
Feb 29, 2024	☽ POST	+8.97%	open_in_new
Nov 09, 2023	☽ POST	+0.21%	open_in_new
Aug 11, 2023	☀ PRE	-4.76%	open_in_new
May 11, 2023	☀ PRE	-3.66%	open_in_new
Mar 02, 2023	☀ PRE	-1.27%	open_in_new
Nov 03, 2022	☀ PRE	-6.56%	open_in_new
Aug 04, 2022	☀ PRE	+6.41%	open_in_new
May 05, 2022	☀ PRE	+1.28%	open_in_new
Mar 08, 2022	☀ PRE	+3.86%	open_in_new
Nov 04, 2021	☀ PRE	-1.03%	open_in_new
Aug 05, 2021	☀ PRE	+3.18%	open_in_new
May 10, 2021	☀ PRE	-2.76%	open_in_new
Mar 18, 2021	☀ PRE	-3.61%	open_in_new
Nov 05, 2020	☀ PRE	+8.08%	open_in_new
Aug 10, 2020	☀ PRE	-3.01%	open_in_new
May 07, 2020	☀ PRE	+5.5%	open_in_new
Feb 24, 2020	☀ PRE	-5.72%	open_in_new
Nov 06, 2019	☀ PRE	-2.07%	open_in_new
Aug 06, 2019	☀ PRE	-2.83%	open_in_new
May 07, 2019	☀ PRE	-3.14%	open_in_new
Mar 07, 2019	☽ POST	-2.44%	open_in_new
Nov 08, 2018	☀ PRE	+4.85%	open_in_new
Aug 09, 2018	☀ PRE	+5.86%	open_in_new
May 08, 2018	☀ PRE	+1.01%	open_in_new
Mar 13, 2018	☀ PRE	+0.23%	open_in_new
Nov 07, 2017	☽ POST	-3.71%	open_in_new
Aug 09, 2017	☽ POST	+0.34%	open_in_new
May 09, 2017	☀ PRE	-2.95%	open_in_new
Mar 23, 2017	☽ POST	+0.68%	open_in_new
Nov 09, 2016	☀ PRE	-1.84%	open_in_new
Aug 09, 2016	☀ PRE	+3.04%	open_in_new
May 19, 2016	☀ PRE	-0.67%	open_in_new

event

Earnings Count

Total earnings in dataset

trending_up

Avg Abs. Movement

±3.79%

Avg % price change on earnings

description

SEC Filings

View

Browse all SEC filings

account_balance

Institutional ownership

Holdings as of Mar 31, 2026 · SEC 13-F

View all 21 →

Funds holding

$691843807

Total value held

Buying

16 added · 5 reduced

Blackrock, Inc.

$278490385 -0.02%

State Street Corp

$131498644 +15.21%

Janus Henderson Group Plc

$83586597 NEW BUY

Bank Of America Corp /De/

$61945011 +192.59%

Franklin Resources Inc

$44530096 -20.41%

SEC Filing Types

Recent SEC Filings

10 most recent

Form	Date Filed	View on EDGAR
4	20260702	open_in_new SEC.gov
4	20260702	open_in_new SEC.gov
4	20260702	open_in_new SEC.gov
144	20260701	open_in_new SEC.gov
4	20260626	open_in_new SEC.gov
S-3ASR	20260626	open_in_new SEC.gov
144	20260625	open_in_new SEC.gov
144	20260623	open_in_new SEC.gov
4	20260623	open_in_new SEC.gov
4	20260623	open_in_new SEC.gov

Frequently asked about SYRE earnings

When does Spyre Therapeutics, Inc. report earnings next? expand_more

Spyre Therapeutics, Inc. (SYRE)'s next earnings date is approximate for 2026-08-11. This is a prediction based on its historical quarterly reporting pattern, not a company-confirmed date.

How much does SYRE stock move after earnings? expand_more

Over 42 reports, SYRE has moved an average of ±3.79% the session after earnings, closing higher 54.8% of the time.

What was SYRE's biggest post-earnings move? expand_more

SYRE's largest post-earnings gain on record was +14.28% on Feb 19, 2026, and its largest decline was -6.56% on Nov 03, 2022.

Where can I find Spyre Therapeutics, Inc.'s SEC filings? expand_more

All of Spyre Therapeutics, Inc.'s SEC filings — 10-K, 10-Q, 8-K and more — are listed in the SEC filings section on this page, each linking to the original document on SEC.gov.