Spyre Therapeutics, Inc. (SYRE)

Typically moves ±3.72% on earnings

EARNINGS ANALYTICS

event_upcoming Est. Next Earnings: 2026-11-11 ESTIMATED

Spyre Therapeutics, Inc. (SYRE) has a 43-report earnings history dating back to May 19, 2016. Its average absolute post-earnings move is ±3.72%, and 53.5% of those reactions were positive. Its largest post-earnings gain was +14.28% (Feb 19, 2026) and its largest decline was -6.56% (Nov 03, 2022). The next earnings report is predicted for 2026-11-11 (estimated).

Earnings reactions

How SYRE moved on each past earnings report.

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Earnings Impact

Total Earnings

Avg Abs. Movement

±3.72%

Positive %

53.5%

Negative %

46.5%

Historical Earnings Statistics

Date	Timing	Earnings move	SEC Filing
Aug 04, 2026	☽ POST	-0.63%	open_in_new
May 05, 2026	☀ PRE	+2.73%	open_in_new
Apr 13, 2026	☽ POST	+1.17%	open_in_new
Feb 19, 2026	☽ POST	+14.28%	open_in_new
Nov 04, 2025	☽ POST	-0.57%	open_in_new
Aug 05, 2025	☽ POST	-5.39%	open_in_new
May 08, 2025	☽ POST	+9.64%	open_in_new
Feb 27, 2025	☽ POST	+7.24%	open_in_new
Nov 07, 2024	☽ POST	+5%	open_in_new
Aug 07, 2024	☽ POST	+2.85%	open_in_new
May 09, 2024	☽ POST	+4.94%	open_in_new
Feb 29, 2024	☽ POST	+8.97%	open_in_new
Nov 09, 2023	☽ POST	+0.21%	open_in_new
Aug 11, 2023	☀ PRE	-4.76%	open_in_new
May 11, 2023	☀ PRE	-3.66%	open_in_new
Mar 02, 2023	☀ PRE	-1.27%	open_in_new
Nov 03, 2022	☀ PRE	-6.56%	open_in_new
Aug 04, 2022	☀ PRE	+6.41%	open_in_new
May 05, 2022	☀ PRE	+1.28%	open_in_new
Mar 08, 2022	☀ PRE	+3.86%	open_in_new
Nov 04, 2021	☀ PRE	-1.03%	open_in_new
Aug 05, 2021	☀ PRE	+3.18%	open_in_new
May 10, 2021	☀ PRE	-2.76%	open_in_new
Mar 18, 2021	☀ PRE	-3.61%	open_in_new
Nov 05, 2020	☀ PRE	+8.08%	open_in_new
Aug 10, 2020	☀ PRE	-3.01%	open_in_new
May 07, 2020	☀ PRE	+5.5%	open_in_new
Feb 24, 2020	☀ PRE	-5.72%	open_in_new
Nov 06, 2019	☀ PRE	-2.07%	open_in_new
Aug 06, 2019	☀ PRE	-2.83%	open_in_new
May 07, 2019	☀ PRE	-3.14%	open_in_new
Mar 07, 2019	☽ POST	-2.44%	open_in_new
Nov 08, 2018	☀ PRE	+4.85%	open_in_new
Aug 09, 2018	☀ PRE	+5.86%	open_in_new
May 08, 2018	☀ PRE	+1.01%	open_in_new
Mar 13, 2018	☀ PRE	+0.23%	open_in_new
Nov 07, 2017	☽ POST	-3.71%	open_in_new
Aug 09, 2017	☽ POST	+0.34%	open_in_new
May 09, 2017	☀ PRE	-2.95%	open_in_new
Mar 23, 2017	☽ POST	+0.68%	open_in_new
Nov 09, 2016	☀ PRE	-1.84%	open_in_new
Aug 09, 2016	☀ PRE	+3.04%	open_in_new
May 19, 2016	☀ PRE	-0.67%	open_in_new

event

Earnings Count

Total earnings in dataset

trending_up

Avg Abs. Movement

±3.72%

Avg % price change on earnings

description

SEC Filings

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Browse all SEC filings

account_balance

Institutional ownership

Holdings as of Jun 30, 2026 · SEC 13-F

View all 29 →

Funds holding

$1757052184

Total value held

Buying

27 added · 2 reduced

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SEC Filing Types

Recent SEC Filings

10 most recent

Form	Date Filed	View on EDGAR
8-K	20260908	open_in_new SEC.gov
4	20260903	open_in_new SEC.gov
4	20260903	open_in_new SEC.gov
4	20260903	open_in_new SEC.gov
144	20260901	open_in_new SEC.gov
8-K	20260825	open_in_new SEC.gov
SCHEDULE 13G/A	20260814	open_in_new SEC.gov
SCHEDULE 13G/A	20260814	open_in_new SEC.gov
4	20260810	open_in_new SEC.gov
144	20260807	open_in_new SEC.gov

Frequently asked about SYRE earnings

When does Spyre Therapeutics, Inc. report earnings next? expand_more

Spyre Therapeutics, Inc. (SYRE)'s next earnings date is estimated for 2026-11-11. This is a prediction based on its historical quarterly reporting pattern, not a company-confirmed date.

How much does SYRE stock move after earnings? expand_more

Over 43 reports, SYRE has moved an average of ±3.72% the session after earnings, closing higher 53.5% of the time.

What was SYRE's biggest post-earnings move? expand_more

SYRE's largest post-earnings gain on record was +14.28% on Feb 19, 2026, and its largest decline was -6.56% on Nov 03, 2022.

Where can I find Spyre Therapeutics, Inc.'s SEC filings? expand_more

All of Spyre Therapeutics, Inc.'s SEC filings — 10-K, 10-Q, 8-K and more — are listed in the SEC filings section on this page, each linking to the original document on SEC.gov.